S-adenosylmethionine

From Citizendium, the Citizens' Compendium

Jump to: navigation, search


This article is a stub and thus not approved.
Main Article
Talk
Related Articles  [?]
Bibliography  [?]
External Links  [?]
 
http://en.citizendium.org/wiki?title=S-adenosylmethionine&printable=yes
This is a draft article, under development and not meant to be cited but you can help to improve it. These unapproved articles are subject to a disclaimer.

In biology and medicine, S-adenosylmethionine is a "physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease."[1]

S-adenosylmethionine's role in treating liver disease is uncertain.[2]

S-adenosylmethionine may help osteoarthritis[3][4][5][6][7]; however, the limited research may be affected by publication bias.

References

  1. ↑ Anonymous, (2009) S-adenosylmethionine (English). Medical Subject Headings. U.S. National Library of Medicine.
  2. ↑ Rambaldi A, Gluud C (2006). S-adenosyl-L-methionine for alcoholic liver diseases. Cochrane Database Syst Rev (2): CD002235. DOI:10.1002/14651858.CD002235.pub2. PMID 16625556.
  3. ↑ Hardy ML, Coulter I, Morton SC, et al (August 2003). "S-adenosyl-L-methionine for treatment of depression, osteoarthritis, and liver disease". Evid Rep Technol Assess (Summ) (64): 1–3. PMID 12899148. ACP Journal Club review
  4. ↑ Najm WI, Reinsch S, Hoehler F, Tobis JS, Harvey PW (February 2004). S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord 5: 6. DOI:10.1186/1471-2474-5-6. PMID 15102339. PMC 387830.
  5. ↑ Müller-Fassbender H (November 1987). "Double-blind clinical trial of S-adenosylmethionine versus ibuprofen in the treatment of osteoarthritis". Am. J. Med. 83 (5A): 81–3. PMID 3318445.
  6. ↑ Vetter G (November 1987). "Double-blind comparative clinical trial with S-adenosylmethionine and indomethacin in the treatment of osteoarthritis". Am. J. Med. 83 (5A): 78–80. PMID 3318444.
  7. ↑ König B (November 1987). "A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis". Am. J. Med. 83 (5A): 89–94. PMID 3318447.
Retrieved from "http://en.citizendium.org/wiki/S-adenosylmethionine"
Views
Personal tools