Rosuvastatin

From Citizendium, the Citizens' Compendium

Rosuvastatin, marketed as Crestor, is a type II statin used to treat high cholesterol levels (hypercholesterolemia), prevent heart attacks and strokes, and to diminish the formation of arterial plaque. It is a HMG-CoA reductase inhibitor that decreases the conversion of HMG-CoA to mevalonate, a key chemical precursor of cholesterol. It is related to other type II statins such as fluvastatin and atorvastatin.

Its official chemical IUPAC name is (E,3R,5R)-7-[4-(4-fluorophenyl)-2-(methyl-methylsulfonylamino)-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid and its chemical formula is C₂₂H₂₈FN₃O₆S.

External links

The most up-to-date information about Rosuvastatin and other drugs can be found at the following sites.

• Rosuvastatin - FDA approved drug information (drug label) from DailyMed (U.S. National Library of Medicine).
• Rosuvastatin - Drug information for consumers from MedMaster (U.S. National Library of Medicine).
• Rosuvastatin - Detailed information from DrugBank.